Sulphomucins favour adhesion of Helicobacter pylori to metaplastic gastric mucosa
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori, intestinal metaplasia, and the accuracy of biopsies in metaplastic gastric mucosa
The identification and eradication of Helicobacter Pylori (HP) is vital to prevent gastric cancer. After the detection of the HP colonization, accompanying histopathological findings belonging the gastric carcinogenesis should also be considered. According to the widely accepted proofs, although the presence of HP colonization initiates the sequential changes of carcinogenesis, the success rate...
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Adhesion of Helicobacter pylori to the gastric mucosa is a necessary prerequisite for the pathogenesis of H. pylori-related diseases. In this study, we investigated the GalNAcβ1-4GlcNAc motif (also known as N,N'-diacetyllactosediamine [lacdiNAc]) carried by MUC5AC gastric mucins as the target for bacterial binding to the human gastric mucosa. The expression of LacdiNAc carried by gastric mucins...
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Helicobacter pylori is the main pathogenic bacterium involved in chronic gastritis and peptic ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the pathogenicity of H. pylori and the mechanism by which it colonizes the gastric mucosa. An increasing number of in vivo and in vitro studies demonstrate that H. pylori can invade and proliferate in epithelial cells, sugges...
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Helicobacter pylori (H. pylori) related gastric infection is highly prevalent in developing countries. Prevalence of bacterium in dental plaque from these regions is also reported to be high, but association between simultaneous colonization of H. pylori in both these sites has not been established yet. Aim of this paper is to review possible association between simultaneous oral and gastric H....
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1999
ISSN: 0021-9746
DOI: 10.1136/jcp.52.2.137